Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond.

This review summarizes our current understanding of catechol-o-methyltransferase (COMT) and how it relates to brain function and schizophrenia. We begin by considering the COMT gene, its transcripts and proteins, and its relevance for central catecholamine function. We then describe how variation in...

ver descrição completa

Detalhes bibliográficos
Main Authors: Tunbridge, E, Harrison, P, Weinberger, DR
Formato: Journal article
Idioma:English
Publicado em: 2006