Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond.

This review summarizes our current understanding of catechol-o-methyltransferase (COMT) and how it relates to brain function and schizophrenia. We begin by considering the COMT gene, its transcripts and proteins, and its relevance for central catecholamine function. We then describe how variation in...

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Những tác giả chính: Tunbridge, E, Harrison, P, Weinberger, DR
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2006