Plasmodium falciparum PfEMP1 modulates monocyte/macrophage transcription factor activation, and cytokine and chemokine responses
Immunity to Plasmodium falciparum malaria is slow to develop, and it is often asserted that malaria suppresses host immunity, although this is poorly understood and the molecular basis for such activity remains unknown. P. falciparum Erythrocyte Membrane Protein 1 (PfEMP1) is a virulence factor that...
Main Authors: | Sampaio, N, Eriksson, E, Schofield, L |
---|---|
Format: | Journal article |
Published: |
American Society for Microbiology
2017
|
Similar Items
-
Extracellular vesicles from early stage Plasmodium falciparum‐infected red blood cells contain PfEMP1 and induce transcriptional changes in human monocytes
by: Sampaio, N, et al.
Published: (2018) -
The kinetics of antibody binding to <it>Plasmodium falciparum </it>VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs
by: Arnot David E, et al.
Published: (2010-04-01) -
PfEMP1 expression is reduced on the surface of knobless Plasmodium falciparum infected erythrocytes.
by: Horrocks, P, et al.
Published: (2005) -
Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed
by: Barfod, L, et al.
Published: (2015) -
Identifying genetic determinants of impaired PfEMP1 export in Plasmodium falciparum-infected erythrocytes
by: Neal, AT
Published: (2014)