The variable number of tandem repeats upstream of the insulin gene is a susceptibility locus for latent autoimmune diabetes in adults.
The etiopathological relationship between latent autoimmune diabetes in adults (LADA) and classical type 1 (insulin dependent) diabetes remains unclear. Variation at the insulin gene variable number of tandem repeats (VNTR) minisatellite influences susceptibility to type 1 diabetes, but studies in L...
Main Authors: | Desai, M, Zeggini, E, Horton, V, Owen, K, Hattersley, A, Levy, J, Hitman, G, Walker, M, Holman, R, McCarthy, M, Clark, A |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2006
|
Similar Items
-
Susceptibility for latent autoimmune diabetes in adults (LADA) is determined by variation at the 1DDM2 (insulin-gene) locus in white Caucasian patients from UK repositories
by: Desai, M, et al.
Published: (2005) -
Susceptibility effects of variation at the IDDM2 (Insulin-gene) locus in latent autoimmune diabetes in adults (LADA).
by: Desai, M, et al.
Published: (2003) -
Variation at the insulin VNTR locus but not the CTLA-4 locus is associated with age of onset and need for insulin therapy in latent autoimmune diabetes in adults (LADA)
by: Horton, V, et al.
Published: (2001) -
An association analysis of the HLA gene region in latent autoimmune diabetes in adults.
by: Desai, M, et al.
Published: (2007) -
Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles.
by: Huxtable, S, et al.
Published: (2000)