Analysis of the substrate-binding site of human carbonyl reductases CBR1 and CBR3 by site-directed mutagenesis.

Analysis of the substrate-binding site of human carbonyl reductases CBR1 and CBR3 by site-directed mutagenesis.

Pokaži ostale verzije (1)

Human carbonyl reductase is a member of the short-chain dehydrogenase/reductase (SDR) protein superfamily and is known to play an important role in the detoxification of xenobiotics bearing a carbonyl group. The two monomeric NADPH-dependent human isoforms of cytosolic carbonyl reductase CBR1 and CB...

Bibliografski detalji
Glavni autori:	El-Hawari, Y, Favia, A, Pilka, E, Kisiela, M, Oppermann, U, Martin, H, Maser, E
Format:	Journal article
Jezik:	English
Izdano:	2009
Teme:	DNA Primers Base Sequence chemistry Models, Molecular Kinetics Substrate Specificity genetics Humans Sequence Homology, Amino Acid Binding Sites DNA, Complementary Alcohol Oxidoreductases Amino Acid Sequence metabolism Mutagenesis, Site-Directed isolation and purification Biocatalysis Molecular Sequence Data

Slični predmeti

Analysis of the substrate-binding site of human carbonyl reductases CBR1 and CBR3 by site-directed mutagenesis.
od: El-Hawari, Y, i dr.
Izdano: (2009)

Comprehensive site-directed mutagenesis of L-2-Halo acid dehalogenase to probe catalytic amino acid residues/
od: 497336 Kurihara, Tatsuo, i dr.

Characterization of the human carbonyl reductase 3 (CBR3) by site-directed mutagenesis
od: El-Hawari, Y, i dr.
Izdano: (2008)

Comprehensive site-directed mutagenesis of L-2-halo acid dehalogenase to probe catalytic amino acid residues/
od: 497336 Kurihara, Tatsuo, i dr.

REMP software to introduce a screening REstriction site in site-directed Mutagenesis Primer
od: Madhavi Latha Yadav Bangaru, PhD, i dr.
Izdano: (2021-12-01)

Prediction of Metal Ion Binding Sites in Proteins from Amino Acid Sequences by Using Simplified Amino Acid Alphabets and Random Forest Model
od: Suresh Kumar
Izdano: (2017-12-01)

Mechanism and substrate recognition of human holo ACP synthase.
od: Bunkoczi, G, i dr.
Izdano: (2007)

Structure of the pseudokinase VRK3 reveals a degraded catalytic site, a highly conserved kinase fold, and a putative regulatory binding site.
od: Scheeff, E, i dr.
Izdano: (2009)

Structural basis for substrate specificity in human monomeric carbonyl reductases.
od: Pilka, E, i dr.
Izdano: (2009)

Sequence analysis in molecular biology : treasure trove or trivial pursuit/
od: 458233 Von Heijne, Gunnar
Izdano: (1987)

Computer analysis of sequence data /
od: Griffin, Annette M., i dr.
Izdano: (1994)

Computer analysis of sequence data /
od: Griffin, Annette M., i dr.
Izdano: (1994)

Mammalian ETCHbox homeodomains
od: Lewin, T D, i dr.
Izdano: (2021)

High-throughput detection of T-DNA insertion sites for multiple transgenes in complex genomes
od: Brianne Edwards, i dr.
Izdano: (2022-10-01)

Database annotation in molecular biology /
od: Lesk, Arthur M.
Izdano: (2005)

Nucleotide structure of prion protein gene in Egyptian camels
od: Sekena H. Abdel-Aziem, i dr.
Izdano: (2019-01-01)

Investigating peptide sequence variations for ‘double-click’ stapled p53 peptides
od: Lau, Yu Heng, i dr.
Izdano: (2016)

High-sensitivity sequencing with a gas-phase sequenator /
od: Hunkapiller, Michael W.

Application of string kernel on protein sequence classification /
od: Nazar Mustafa Zaki, i dr.
Izdano: (2003)

Techniques in protein chemistry/
od: Hugli, Tony E., i dr.
Izdano: (1989)

Protein structure prediction /
od: Zaki, Mohammed J., 1971-, i dr.
Izdano: (2008)

Methods in protein structure analysis /
od: Atassi, M. Zouhair, i dr.
Izdano: (1995)

Mathematical models of random arrangement of amino acids in the sequence
od: Alvydas Špokas, i dr.
Izdano: (2004-12-01)

Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A
od: Kochan, G, i dr.
Izdano: (2009)

Practical bioinformatics /
od: Bujnicki, Janusz M.
Izdano: (2008)

Efficient cloning of linear DNA inserts (ECOLI) into plasmids using site-directed mutagenesis
od: Petra Paclikova, i dr.
Izdano: (2024-09-01)

A Highly Efficient In Vitro Site-directed Mutagenesis Protocol for Introducing  Multiple-site Mutations into Target Genes
od: Fanrong MENG, i dr.
Izdano: (2014-06-01)

Introduction to protein structure /
od: 217825 Branden, Carl, i dr.
Izdano: (1999)

The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation.
od: Baumli, S, i dr.
Izdano: (2008)

Characterization of human DHRS6, an orphan short chain dehydrogenase/reductase enzyme: a novel, cytosolic type 2 R-beta-hydroxybutyrate dehydrogenase
od: Guo, K, i dr.
Izdano: (2006)

Bioinformatics : sequence and genome analysis /
od: 223126 Mount, David W.
Izdano: (2004)

Bioinformatics : a practical guide to the analysis of genes and proteins /
od: 333969 Baxevanis, Andreas D., i dr.
Izdano: (2001)

Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid synthases.
od: Bunkoczi, G, i dr.
Izdano: (2009)

Practical bioinformatics /
od: Bujnicki, Janusz M.
Izdano: (2004)

A Practical guide to protein and peptide purification for microsequencing /
od: Matsudaira, Paul T.
Izdano: (1989)

Laboratory methodology in biochemistry : amino acid analysis and protein sequencing/
od: Fini, Carlo, i dr.
Izdano: (1990)

Methods of protein microcharacterization : an practical handbook/
od: Shively, John E.
Izdano: (1986)

Amino acid sequences of proteins from Leptospira serovar pomona
od: Alves Selmo F, i dr.
Izdano: (2000-01-01)

Analysis of two duplications of the LDL receptor gene affectingintracellular transport, catabolism, and surface binding of the LDLreceptor
od: Dilip.D. Patel, i dr.
Izdano: (1998-07-01)

Deep learning for HGT insertion sites recognition
od: Chen Li, i dr.
Izdano: (2020-12-01)