Analysis of the substrate-binding site of human carbonyl reductases CBR1 and CBR3 by site-directed mutagenesis.

Analysis of the substrate-binding site of human carbonyl reductases CBR1 and CBR3 by site-directed mutagenesis.

Diğer sürümleri göster (1)

Human carbonyl reductase is a member of the short-chain dehydrogenase/reductase (SDR) protein superfamily and is known to play an important role in the detoxification of xenobiotics bearing a carbonyl group. The two monomeric NADPH-dependent human isoforms of cytosolic carbonyl reductase CBR1 and CB...

Detaylı Bibliyografya
Asıl Yazarlar:	El-Hawari, Y, Favia, A, Pilka, E, Kisiela, M, Oppermann, U, Martin, H, Maser, E
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2009
Konular:	DNA Primers Base Sequence chemistry Models, Molecular Kinetics Substrate Specificity genetics Humans Sequence Homology, Amino Acid Binding Sites DNA, Complementary Alcohol Oxidoreductases Amino Acid Sequence metabolism Mutagenesis, Site-Directed isolation and purification Biocatalysis Molecular Sequence Data

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