The magnitude and breadth of hepatitis C virus-specific CD8+ T cells depend on absolute CD4+ T-cell count in individuals coinfected with HIV-1.

The magnitude and breadth of hepatitis C virus-specific CD8+ T cells depend on absolute CD4+ T-cell count in individuals coinfected with HIV-1.

CD8(+) T-cell responses are an essential antiviral host defense in persistent viral infections, and their sustained effectiveness is thought to be critically dependent on CD4(+) T-helper cells. To determine the relationship between HIV-1-induced CD4(+) T-cell depletion and hepatitis C virus (HCV)-sp...

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Bibliographic Details
Main Authors:	Kim, A, Lauer, G, Ouchi, K, Addo, M, Lucas, M, Schulze Zur Wiesch, J, Timm, J, Boczanowski, M, Duncan, J, Wurcel, A, Casson, D, Chung, RT, Draenert, R, Klenerman, P, Walker, B
Format:	Journal article
Language:	English
Published:	2005

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