Emergence of a distinct HIV-specific IL-10-producing CD8+ T-cell subset with immunomodulatory functions during chronic HIV-1 infection.

Emergence of a distinct HIV-specific IL-10-producing CD8+ T-cell subset with immunomodulatory functions during chronic HIV-1 infection.

Interleukin-10 (IL-10) plays a key role in regulating proinflammatory immune responses to infection but can interfere with pathogen clearance. Although IL-10 is upregulated throughout HIV-1 infection in multiple cell subsets, whether this is a viral immune evasion strategy or an appropriate response...

Bibliografiset tiedot
Päätekijät:	Clutton, G, Yang, H, Hancock, G, Sande, N, Holloway, C, Angus, B, von Delft, A, Barnes, E, Borrow, P, Pellegrino, P, Williams, I, McMichael, A, Dorrell, L
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	2013

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