Requirement of mature dendritic cells for efficient activation of influenza A-specific memory CD8+ T cells.

It is critical to identify the developmental stage of dendritic cells (DCs) that is most efficient at inducing CD8+ T cell responses. Immature DCs can be generated from monocytes with GM-CSF and IL-4, while maturation is accomplished by the addition of stimuli such as monocyte-conditioned medium, CD...

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Bibliographic Details
Main Authors: Larsson, M, Messmer, D, Somersan, S, Fonteneau, J, Donahoe, S, Lee, M, Dunbar, P, Cerundolo, V, Julkunen, I, Nixon, D, Bhardwaj, N
Format: Journal article
Language:English
Published: 2000