Human invariant NKT cells display alloreactivity instructed by invariant TCR-CD1d interaction and killer Ig receptors
Invariant NKT (iNKT) cells are a subset of highly conserved immunoregulatory T cells that modify a variety of immune responses, including alloreactivity. Central to their function is the interaction of the invariant TCR with glycosphingolipid (GSL) ligands presented by the nonpolymorphic MHC class I...
Main Authors: | Patterson, S, Chaidos, A, Neville, D, Poggi, A, Butters, T, Roberts, I, Karadimitris, A |
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Format: | Journal article |
Language: | English |
Published: |
2008
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