CDR3 loop flexibility contributes to the degeneracy of TCR recognition.

CDR3 loop flexibility contributes to the degeneracy of TCR recognition.

T cell receptor (TCR) binding degeneracy lies at the heart of several physiological and pathological phenomena, yet its structural basis is poorly understood. We determined the crystal structure of a complex involving the BM3.3 TCR and an octapeptide (VSV8) bound to the H-2K(b) major histocompatibil...

書誌詳細
主要な著者:	Reiser, J, Darnault, C, Grégoire, C, Mosser, T, Mazza, G, Kearney, A, Van Der Merwe, P, Fontecilla-Camps, J, Housset, D, Malissen, B
フォーマット:	Journal article
言語:	English
出版事項:	2003

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