Twisting transition between crystalline and fibrillar phases of aggregated peptides.
We study two distinctly ordered condensed phases of polypeptide molecules, amyloid fibrils and amyloidlike microcrystals, and the first-order twisting phase transition between these two states. We derive a single free-energy form which connects both phases. Our model identifies relevant degrees of f...
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Detalhes bibliográficos
| Principais autores: |
Knowles, T,
De Simone, A,
Fitzpatrick, A,
Baldwin, A,
Meehan, S,
Rajah, L,
Vendruscolo, M,
Welland, M,
Dobson, C,
Terentjev, E |
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| Formato: | Journal article
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| Idioma: | English |
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| Publicado em: |
2012
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