An intronic Flk1 enhancer directs arterial-specific expression via RBPJ-mediated venous repression

<p>Objective—The vascular endothelial growth factor (VEGF) receptor Flk1 is essential for vascular development, but the signaling and transcriptional pathways by which its expression is regulated in endothelial cells remain unclear. Although previous studies have identified 2 Flk1 regulatory e...

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Váldodahkkit: de Val, S, Sacilotto, N, Nornes, S, Becker, P, Neal, A, Thomas, M, Preece, C, Ratnayaka, I, Davies, B, Liu, K, Bou-Gharios, G
Materiálatiipa: Journal article
Almmustuhtton: American Heart Association 2016