Effects of neutralizing antibodies on escape from CD8+ T-cell responses in HIV-1 infection.
Despite substantial advances in our knowledge of immune responses against HIV-1 and of its evolution within the host, it remains unclear why control of the virus eventually breaks down. Here, we present a new theoretical framework for the infection dynamics of HIV-1 that combines antibody and CD8(+)...
Main Authors: | Wikramaratna, P, Lourenço, J, Klenerman, P, Pybus, O, Gupta, S |
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Format: | Journal article |
Language: | English |
Published: |
Royal Society
2015
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Subjects: |
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