Effects of neutralizing antibodies on escape from CD8+ T-cell responses in HIV-1 infection.

Despite substantial advances in our knowledge of immune responses against HIV-1 and of its evolution within the host, it remains unclear why control of the virus eventually breaks down. Here, we present a new theoretical framework for the infection dynamics of HIV-1 that combines antibody and CD8(+)...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Wikramaratna, P, Lourenço, J, Klenerman, P, Pybus, O, Gupta, S
التنسيق: Journal article
اللغة:English
منشور في: Royal Society 2015
الموضوعات: