Genomic analyses from non-invasive prenatal testing reveal genetic associations, patterns of viral infections, and Chinese population history

We analyze whole-genome sequencing data from 141,431 Chinese women generated for non-invasive prenatal testing (NIPT). We use these data to characterize the population genetic structure and to investigate genetic associations with maternal and infectious traits. We show that the present day distribu...

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Bibliographic Details
Main Authors: Liu, S, Huang, S, Chen, F, Zhao, L, Yuan, Y, Francis, S, Fang, L, Li, Z, Lin, L, Liu, R, Zhang, Y, Xu, H, Li, S, Zhou, Y, Davies, R, Liu, Q, Walters, R, Lin, K, Ju, J, Korneliussen, T, Yang, M, Fu, Q, Wang, J, Zhou, L, Krogh, A, Zhang, H, Wang, W, Chen, Z, Cai, Z, Yin, Y, Yang, H, Mao, M, Shendure, J, Albrechtsen, A, Jin, X, Nielsen, R, Xu, X
Format: Journal article
Language:English
Published: Cell Press 2018