Horizontal gene transfer rate is not the primary determinant of observed antibiotic resistance frequencies in Streptococcus pneumoniae
The extent to which evolution is constrained by the rate at which horizontal gene transfer (HGT) allows DNA to move between genetic lineages is an open question, which we address in the context of antibiotic resistance in Streptococcus pneumoniae. We analyze microbiological, genomic, and epidemiolog...
Main Authors: | Lehtinen, S, Chewapreecha, C, Lees, J, Hanage, WP, Lipsitch, M, Croucher, NJ, Bentley, SD, Turner, P, Fraser, C, Mostowy, RJ |
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Format: | Journal article |
Language: | English |
Published: |
American Association for the Advancement of Science
2020
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