A phenome-wide association study of a lipoprotein associated phospholipase A2 loss-of-function variant in 90 000 Chinese adults

<h4>Background</h4> <p>Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been implicated in development of atherosclerosis, however, recent randomised trials of Lp-PLA2 inhibition reported no beneficial effects on vascular diseases. In East Asians, a loss-of-function variant in...

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Bibliographic Details
Main Authors: Millwood, I, Bennett, D, Walters, R, Clarke, R, Waterworth, D, Johnson, T, Chen, Y, Yang, L, Guo, Y, Bian, Z, Hacker, A, Yeo, A, Parish, S, Hill, M, Chissoe, S, Peto, R, Cardon, L, Collins, R, Li, L, Chen, Z
Format: Journal article
Published: Oxford University Press 2016