Genotypic and phenotypic changes during culture of a multinucleoside-resistant human immunodeficiency virus type 1 strain in the presence and absence of additional reverse transcriptase inhibitors.
The observation that human immunodeficiency virus type 1 (HIV-1) mutations conferring resistance to one reverse transcriptase (RT) inhibitor may suppress resistance to other RT inhibitors provides a rationale for treating HIV-1 with certain RT inhibitor combinations. We examined phenotypic and genot...
Main Authors: | Shafer, R, Winters, M, Iversen, A, Merigan, T |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1996
|
Similar Items
-
A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance.
by: Larder, B, et al.
Published: (1999) -
Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy.
by: Iversen, A, et al.
Published: (1996) -
In vitro HIV-1 evolution in response to triple reverse transcriptase inhibitors & in silico phenotypic analysis.
by: Barbara A Rath, et al.
Published: (2013-01-01) -
STRUCTURAL STUDIES ON HUMAN-IMMUNODEFICIENCY-VIRUS REVERSE-TRANSCRIPTASE
by: Stammers, D, et al.
Published: (1990) -
Identification of the minimal conserved structure of the HIV reverse transcriptase under the presence and absence of drug pressure
by: Ceccherini-Silberstein, F, et al.
Published: (2003)