Dinucleotide-sensing proteins: linking signaling networks and regulating transcription.
Differential binding of dinucleotides to key regulatory proteins can modulate their interactions with other proteins and, in some cases, can signal fluctuations in the cellular redox state, to produce changes in transcription and physiological state. The dinucleotide-binding proteins human HSCARG an...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2008
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| _version_ | 1797063517650550784 |
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| author | Lamb, H Stammers, D Hawkins, A |
| author_facet | Lamb, H Stammers, D Hawkins, A |
| author_sort | Lamb, H |
| collection | OXFORD |
| description | Differential binding of dinucleotides to key regulatory proteins can modulate their interactions with other proteins and, in some cases, can signal fluctuations in the cellular redox state, to produce changes in transcription and physiological state. The dinucleotide-binding proteins human HSCARG and yeast transcription repressor Gal80p are examples that offer exciting glimpses into the potential for dinucleotide-sensing proteins to couple fluctuations in dinucleotide ratios to changes in transcription and to act as networking agents linking different classes of signaling molecules. |
| first_indexed | 2024-03-06T21:01:01Z |
| format | Journal article |
| id | oxford-uuid:3ae2f13a-ef8a-4ec4-a100-e1e11a593545 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:01:01Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:3ae2f13a-ef8a-4ec4-a100-e1e11a5935452022-03-26T14:04:17ZDinucleotide-sensing proteins: linking signaling networks and regulating transcription.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3ae2f13a-ef8a-4ec4-a100-e1e11a593545EnglishSymplectic Elements at Oxford2008Lamb, HStammers, DHawkins, ADifferential binding of dinucleotides to key regulatory proteins can modulate their interactions with other proteins and, in some cases, can signal fluctuations in the cellular redox state, to produce changes in transcription and physiological state. The dinucleotide-binding proteins human HSCARG and yeast transcription repressor Gal80p are examples that offer exciting glimpses into the potential for dinucleotide-sensing proteins to couple fluctuations in dinucleotide ratios to changes in transcription and to act as networking agents linking different classes of signaling molecules. |
| spellingShingle | Lamb, H Stammers, D Hawkins, A Dinucleotide-sensing proteins: linking signaling networks and regulating transcription. |
| title | Dinucleotide-sensing proteins: linking signaling networks and regulating transcription. |
| title_full | Dinucleotide-sensing proteins: linking signaling networks and regulating transcription. |
| title_fullStr | Dinucleotide-sensing proteins: linking signaling networks and regulating transcription. |
| title_full_unstemmed | Dinucleotide-sensing proteins: linking signaling networks and regulating transcription. |
| title_short | Dinucleotide-sensing proteins: linking signaling networks and regulating transcription. |
| title_sort | dinucleotide sensing proteins linking signaling networks and regulating transcription |
| work_keys_str_mv | AT lambh dinucleotidesensingproteinslinkingsignalingnetworksandregulatingtranscription AT stammersd dinucleotidesensingproteinslinkingsignalingnetworksandregulatingtranscription AT hawkinsa dinucleotidesensingproteinslinkingsignalingnetworksandregulatingtranscription |