Deliberate self-harm is associated with allelic variation in the tryptophan hydroxylase gene (TPH A779C), but not with polymorphisms in five other serotonergic genes

Deliberate self-harm is associated with allelic variation in the tryptophan hydroxylase gene (TPH A779C), but not with polymorphisms in five other serotonergic genes

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Background. There is a heritable component to suicidal behaviour, encouraging the search for the associated risk alleles. Given the putative role of the 5-HT (5-hydroxytryptamine; serotonin) system in suicidal behaviour, serotonergic genes are leading candidates. In particular, several studies have...

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Dettagli Bibliografici
Autori principali:	Pooley, E, Houston, K, Hawton, K, Harrison, P
Natura:	Journal article
Lingua:	English
Pubblicazione:	Cambridge University Press 2003
Soggetti:	Suicide research Psychiatry

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