A NEW BASE-STABLE LINKER FOR SOLID-PHASE OLIGONUCLEOTIDE SYNTHESIS
The succinyl-sarcosyl linker (1b), which is stable to prolonged contact with 1,8-diazabicyclo[5.4.0]undec-7-ene but cleaves rapidly with aqueous ammonia, is of potential value in solid-phase oligonucleotide synthesis.
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1989
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| _version_ | 1826267895801315328 |
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| author | Brown, T Pritchard, C Turner, G Salisbury, S |
| author_facet | Brown, T Pritchard, C Turner, G Salisbury, S |
| author_sort | Brown, T |
| collection | OXFORD |
| description | The succinyl-sarcosyl linker (1b), which is stable to prolonged contact with 1,8-diazabicyclo[5.4.0]undec-7-ene but cleaves rapidly with aqueous ammonia, is of potential value in solid-phase oligonucleotide synthesis. |
| first_indexed | 2024-03-06T21:01:16Z |
| format | Journal article |
| id | oxford-uuid:3af5c171-3a21-48c1-81d8-8d5f27da91b2 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:01:16Z |
| publishDate | 1989 |
| record_format | dspace |
| spelling | oxford-uuid:3af5c171-3a21-48c1-81d8-8d5f27da91b22022-03-26T14:04:47ZA NEW BASE-STABLE LINKER FOR SOLID-PHASE OLIGONUCLEOTIDE SYNTHESISJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3af5c171-3a21-48c1-81d8-8d5f27da91b2EnglishSymplectic Elements at Oxford1989Brown, TPritchard, CTurner, GSalisbury, SThe succinyl-sarcosyl linker (1b), which is stable to prolonged contact with 1,8-diazabicyclo[5.4.0]undec-7-ene but cleaves rapidly with aqueous ammonia, is of potential value in solid-phase oligonucleotide synthesis. |
| spellingShingle | Brown, T Pritchard, C Turner, G Salisbury, S A NEW BASE-STABLE LINKER FOR SOLID-PHASE OLIGONUCLEOTIDE SYNTHESIS |
| title | A NEW BASE-STABLE LINKER FOR SOLID-PHASE OLIGONUCLEOTIDE SYNTHESIS |
| title_full | A NEW BASE-STABLE LINKER FOR SOLID-PHASE OLIGONUCLEOTIDE SYNTHESIS |
| title_fullStr | A NEW BASE-STABLE LINKER FOR SOLID-PHASE OLIGONUCLEOTIDE SYNTHESIS |
| title_full_unstemmed | A NEW BASE-STABLE LINKER FOR SOLID-PHASE OLIGONUCLEOTIDE SYNTHESIS |
| title_short | A NEW BASE-STABLE LINKER FOR SOLID-PHASE OLIGONUCLEOTIDE SYNTHESIS |
| title_sort | new base stable linker for solid phase oligonucleotide synthesis |
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