A NEW BASE-STABLE LINKER FOR SOLID-PHASE OLIGONUCLEOTIDE SYNTHESIS

The succinyl-sarcosyl linker (1b), which is stable to prolonged contact with 1,8-diazabicyclo[5.4.0]undec-7-ene but cleaves rapidly with aqueous ammonia, is of potential value in solid-phase oligonucleotide synthesis.

Bibliographic Details
Main Authors:	Brown, T, Pritchard, C, Turner, G, Salisbury, S
Format:	Journal article
Language:	English
Published:	1989

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