T-bet is a key modulator of IL-23-driven pathogenic CD4+ T cell responses in the intestine

T-bet is a key modulator of IL-23-driven pathogenic CD4+ T cell responses in the intestine

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IL-23 is a key driver of pathogenic Th17 cell responses. It has been suggested that the transcription factor T-bet is required to facilitate IL-23-driven pathogenic effector functions; however, the precise role of T-bet in intestinal T cell responses remains elusive. Here, we show that T-bet express...

書目詳細資料
Main Authors:	Krausgruber, T, Schiering, C, Adelmann, K, Harrison, O, Chomka, A, Pearson, C, Ahern, P, Shale, M, Oukka, M, Powrie, F
格式:	Journal article
出版:	Nature Publishing Group 2016

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