Highly diastereoselective anti-dihydroxylation of 3-N,N-dibenzylaminocyclohex-1-ene N-oxide.
Oxidation of 3-N,N-dibenzylaminocyclohex-1-ene N-oxide in the presence of Cl3CCO2H proceeds with high levels of anti-diastereoselectivity (97% de), with no competing side reactions, allowing access to 1,2-anti-2,3-anti-3-aminocyclohexane-1,2-diol after deprotection.
Bibliographic Details
Main Authors: |
Aciro, C,
Davies, S,
Kurosawa, W,
Roberts, P,
Russell, A,
Thomson, J |
Format: | Journal article
|
Language: | English |
Published: |
2009
|