CD40L association with protection from severe malaria.
CD40 ligand (CD40L), a glycoprotein involved in B cell proliferation, antigen presenting cell activation, and Ig class switching, is important in the immune response to infection. Rare coding mutations in CD40L can lead to life-threatening immunodeficiency but the potential for common variants to al...
Main Authors: | Sabeti, P, Usen, S, Farhadian, S, Jallow, M, Doherty, T, Newport, M, Pinder, M, Ward, R, Kwiatkowski, D |
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格式: | Journal article |
語言: | English |
出版: |
2002
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