CD40L association with protection from severe malaria.
CD40 ligand (CD40L), a glycoprotein involved in B cell proliferation, antigen presenting cell activation, and Ig class switching, is important in the immune response to infection. Rare coding mutations in CD40L can lead to life-threatening immunodeficiency but the potential for common variants to al...
Hlavní autoři: | , , , , , , , , |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2002
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