CD40L association with protection from severe malaria.

CD40 ligand (CD40L), a glycoprotein involved in B cell proliferation, antigen presenting cell activation, and Ig class switching, is important in the immune response to infection. Rare coding mutations in CD40L can lead to life-threatening immunodeficiency but the potential for common variants to al...

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Detalhes bibliográficos
Main Authors: Sabeti, P, Usen, S, Farhadian, S, Jallow, M, Doherty, T, Newport, M, Pinder, M, Ward, R, Kwiatkowski, D
Formato: Journal article
Idioma:English
Publicado em: 2002