Vaccine route, dose and type of delivery vector determine patterns of primary CD8+ T cell responses.

Vaccine route, dose and type of delivery vector determine patterns of primary CD8+ T cell responses.

The dynamics of primary CD8+ T cell responses following administration of modified virus Ankara (MVA)- and DNA-vectored vaccines was investigated in a mouse model. To overcome the low frequency of naive antigen-specific precursors and follow the early expansion events, naive CFSE-labelled T cell rec...

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Bibliographic Details
Main Authors:	Estcourt, M, Létourneau, S, Mcmichael, A, Hanke, T
Format:	Journal article
Language:	English
Published:	2005

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