Use of chromoendoscopy versus white light endoscopy for colorectal cancer surveillance in inflammatory bowel disease patients with primary sclerosing cholangitis cohort: A six year experience

Patients with inflammatory bowel disease (IBD) are at increased risk for development of dysplasia and colorectal cancer (CRC), with a further 6-fold increased risk in those with primary sclerosing cholangitis (PSC) versus their non-PSC-IBD counterparts. Preneoplastic tissue in IBD patients is often...

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Bibliographic Details
Main Authors: Hartery, K, Williamson, K, Chapman, R, Atkinson, N, East, J
Format: Conference item
Published: Elsevier 2017
Description
Summary:Patients with inflammatory bowel disease (IBD) are at increased risk for development of dysplasia and colorectal cancer (CRC), with a further 6-fold increased risk in those with primary sclerosing cholangitis (PSC) versus their non-PSC-IBD counterparts. Preneoplastic tissue in IBD patients is often flat and multifocal and may not be appreciated in up to one-third of colonoscopies. The dysplasia yield from surveillance colonoscopy can be improved by spraying dyes that highlight subtle changes in the architecture of the colonic mucosa. Limited data exists on outcomes of chromoendoscopy in PSC-IBD population.