Influence of the HLA-DRB1 locus on susceptibility and severity in rheumatoid arthritis.
We examined HLA-DR genotype risk in 288 patients with rheumatoid arthritis who were carefully categorized for disease severity. Five hundred ethnically-matched bone-marrow donors were controls. A hierarchy of positive allelic associations was noted with DRB1*0401 (p < 10(-38), *0404,8 (p &...
المؤلفون الرئيسيون: | Hall, F, Weeks, D, Camilleri, J, Williams, L, Amos, N, Darke, C, Gibson, K, Pile, K, Wordsworth, B, Jessop, J |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
1996
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مواد مشابهة
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HLA-Dw4 association with rheumatoid arthritis: comment on the article by Nelson et al.
حسب: Pile, K, وآخرون
منشور في: (1995) -
HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class II region.
حسب: Wordsworth, B, وآخرون
منشور في: (1989) -
Does the locus on chromosome 11 implicated in susceptibility to HLA-DR4 dependent type I diabetes mellitus also affect susceptibility to rheumatoid arthritis?
حسب: Pile, K, وآخرون
منشور في: (1992) -
HLA heterozygosity contributes to susceptibility to rheumatoid arthritis.
حسب: Wordsworth, B, وآخرون
منشور في: (1992) -
HLA-DR HETEROZYGOSITY CONTRIBUTES SUSCEPTIBILITY TO SEVERE RHEUMATOID-ARTHRITIS
حسب: Pile, K, وآخرون
منشور في: (1992)