Bites by Russell's viper (Vipera russelli siamensis) in Burma: haemostatic, vascular, and renal disturbances and response to treatment.
Of 123 patients with proved Russell's viper bite, 28% showed no evidence of envenoming, 28% had local swelling alone, but 44% had systemic envenoming manifested by incoagulable blood (100% of those admitted before treatment), thrombocytopenia (26%), spontaneous systemic bleeding (20%), hypotens...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
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1985
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| _version_ | 1797063583197036544 |
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| author | Myint-Lwin Warrell, D Phillips, R Tin-Nu-Swe Tun-Pe Maung-Maung-Lay |
| author_facet | Myint-Lwin Warrell, D Phillips, R Tin-Nu-Swe Tun-Pe Maung-Maung-Lay |
| author_sort | Myint-Lwin |
| collection | OXFORD |
| description | Of 123 patients with proved Russell's viper bite, 28% showed no evidence of envenoming, 28% had local swelling alone, but 44% had systemic envenoming manifested by incoagulable blood (100% of those admitted before treatment), thrombocytopenia (26%), spontaneous systemic bleeding (20%), hypotension (35%), evidence of increased capillary permeability (24%), and oliguria (44%). Patients with systemic envenoming usually had more local swelling than those without, but 5 had no local signs. Snake length correlated with the amount of local swelling, but snakes causing systemic envenoming were no longer than those causing local or no envenoming. Burma Pharmaceutical Industry monospecific antivenom was rapidly effective in restoring blood coagulability but did not prevent the development of renal failure even when given within 4 h of the bite. Hypotension responded to volume expanders (11/19 cases) and dopamine (6/7 cases) but not to naloxone (0/3) or high-dose methylprednisolone (0/5). The 10 deaths (8%) were attributed to hypotension, pituitary haemorrhage, and renal failure. |
| first_indexed | 2024-03-06T21:01:59Z |
| format | Journal article |
| id | oxford-uuid:3b2ec2c8-cfdf-499e-9faf-7017a6084862 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:01:59Z |
| publishDate | 1985 |
| record_format | dspace |
| spelling | oxford-uuid:3b2ec2c8-cfdf-499e-9faf-7017a60848622022-03-26T14:06:07ZBites by Russell's viper (Vipera russelli siamensis) in Burma: haemostatic, vascular, and renal disturbances and response to treatment.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3b2ec2c8-cfdf-499e-9faf-7017a6084862EnglishSymplectic Elements at Oxford1985Myint-LwinWarrell, DPhillips, RTin-Nu-SweTun-PeMaung-Maung-LayOf 123 patients with proved Russell's viper bite, 28% showed no evidence of envenoming, 28% had local swelling alone, but 44% had systemic envenoming manifested by incoagulable blood (100% of those admitted before treatment), thrombocytopenia (26%), spontaneous systemic bleeding (20%), hypotension (35%), evidence of increased capillary permeability (24%), and oliguria (44%). Patients with systemic envenoming usually had more local swelling than those without, but 5 had no local signs. Snake length correlated with the amount of local swelling, but snakes causing systemic envenoming were no longer than those causing local or no envenoming. Burma Pharmaceutical Industry monospecific antivenom was rapidly effective in restoring blood coagulability but did not prevent the development of renal failure even when given within 4 h of the bite. Hypotension responded to volume expanders (11/19 cases) and dopamine (6/7 cases) but not to naloxone (0/3) or high-dose methylprednisolone (0/5). The 10 deaths (8%) were attributed to hypotension, pituitary haemorrhage, and renal failure. |
| spellingShingle | Myint-Lwin Warrell, D Phillips, R Tin-Nu-Swe Tun-Pe Maung-Maung-Lay Bites by Russell's viper (Vipera russelli siamensis) in Burma: haemostatic, vascular, and renal disturbances and response to treatment. |
| title | Bites by Russell's viper (Vipera russelli siamensis) in Burma: haemostatic, vascular, and renal disturbances and response to treatment. |
| title_full | Bites by Russell's viper (Vipera russelli siamensis) in Burma: haemostatic, vascular, and renal disturbances and response to treatment. |
| title_fullStr | Bites by Russell's viper (Vipera russelli siamensis) in Burma: haemostatic, vascular, and renal disturbances and response to treatment. |
| title_full_unstemmed | Bites by Russell's viper (Vipera russelli siamensis) in Burma: haemostatic, vascular, and renal disturbances and response to treatment. |
| title_short | Bites by Russell's viper (Vipera russelli siamensis) in Burma: haemostatic, vascular, and renal disturbances and response to treatment. |
| title_sort | bites by russell s viper vipera russelli siamensis in burma haemostatic vascular and renal disturbances and response to treatment |
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