Use of Minimal Residual Disease Assessment to Redefine Induction Failure in Pediatric Acute Lymphoblastic Leukemia.

Use of Minimal Residual Disease Assessment to Redefine Induction Failure in Pediatric Acute Lymphoblastic Leukemia.

Purpose<br/> Our aim was to determine the role of end-of-induction (EOI) minimal residual disease (MRD) assessment in the identification and stratification of induction failure in patients with pediatric acute lymphoblastic leukemia (ALL) and to identify genetic abnormalities that drive...

Повний опис

Бібліографічні деталі
Автори:	O'Connor, D, Moorman, A, Wade, R, Hancock, J, Tan, R, Bartram, J, Moppett, J, Schwab, C, Patrick, K, Harrison, C, Hough, R, Goulden, N, Vora, A, Samarasinghe, S
Формат:	Journal article
Мова:	English
Опубліковано:	American Society of Clinical Oncology 2017

Схожі ресурси

Genotype-specific MRD interpretation improves stratification in paediatric acute lymphoblastic leukaemia
за авторством: O'Connor, D, та інші
Опубліковано: (2017)

Infection-related mortality in children with acute lymphoblastic leukemia: an analysis of infectious deaths on UKALL2003.
за авторством: O'Connor, D, та інші
Опубліковано: (2014)

Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial.
за авторством: Vora, A, та інші
Опубліковано: (2014)

Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): A randomised controlled trial
за авторством: Vora, A, та інші
Опубліковано: (2014)

Cytogenetic-specific heterogeneity in the kinetics of minimal residual disease (MIRD) clearance in childhood lymphoblastic leukaemia (ALL)
за авторством: Moorman, A, та інші
Опубліковано: (2008)

Treatment reduction for children and young adults with low-risk acute lymphoblastic leukaemia defined by minimal residual disease (UKALL 2003): a randomised controlled trial.
за авторством: Vora, A, та інші
Опубліковано: (2013)

Treatment reduction for children and young adults with low-risk acute lymphoblastic leukaemia defined by minimal residual disease (UKALL 2003): a randomised controlled trial
за авторством: Vora, A, та інші
Опубліковано: (2013)

Down Syndrome is a significant risk factor for infectious deaths in childhood acute lymphoblastic leukaemia: a retrospective analysis of the infectious deaths on UKALL 2003
за авторством: O'Connor, D, та інші
Опубліковано: (2014)

A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia.
за авторством: Moorman, A, та інші
Опубліковано: (2014)

Cytogenetic-specific heterogeneity in the kinetics of minimal residual disease (MRD) clearance in childhood acute lymphoblastic leukaemia (ALL)
за авторством: Moorman, A, та інші
Опубліковано: (2007)

Outcome of Down syndrome associated acute lymphoblastic leukaemia treated on a contemporary protocol.
за авторством: Patrick, K, та інші
Опубліковано: (2014)

Outcome of Down syndrome associated acute lymphoblastic leukaemia treated on a contemporary protocol
за авторством: Patrick, K, та інші
Опубліковано: (2014)

Risk-directed treatment intensification significantly reduces the risk of relapse among children and adolescents with acute lymphoblastic leukemia and intrachromosomal amplification of chromosome 21: a comparison of the MRC ALL97/99 and UKALL2003 trials.
за авторством: Moorman, A, та інші
Опубліковано: (2013)

Outcome for children and young people with Early T-cell precursor acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003
за авторством: Patrick, K, та інші
Опубліковано: (2014)

Outcome for children and young people with Early T-cell precursor acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003.
за авторством: Patrick, K, та інші
Опубліковано: (2014)

UKALL 2003, A Randomised Trial Investigating Treatment Intensification for Children and Young Adults with Minimal Residual Disease Defined High Risk Acute Lymphoblastic Leukaema
за авторством: Vora, A, та інші
Опубліковано: (2012)

Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial.
за авторством: Jenkinson, S, та інші
Опубліковано: (2013)

Incidence and outcome of pancreatitis in children and young adults with acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003
за авторством: Samarasinghe, S, та інші
Опубліковано: (2013)

Incidence and outcome of pancreatitis in children and young adults with acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003.
за авторством: Samarasinghe, S, та інші
Опубліковано: (2013)

Prognostic impact of the absence of biallelic deletion at the TRG locus for pediatric patients with T-cell acute lymphoblastic leukemia treated on the Medical Research Council UK Acute Lymphoblastic Leukemia 2003 trial
за авторством: Nadine Farah, та інші
Опубліковано: (2018-07-01)

Post-Remission MRD Kinetics in Children with Acute Lymphoblastic Leukaemia Receiving Augmented BFM Consolidation Compared with Other Regimens Results of the Medical Research Council Trial UKALL2003.
за авторством: Cutting, R, та інші
Опубліковано: (2008)

IGH@ translocations are prevalent in teenagers and young adults with acute lymphoblastic leukemia and are associated with a poor outcome.
за авторством: Russell, L, та інші
Опубліковано: (2014)

Post-remission MRD kinetics in children with acute lymphoblastic leukaemia receiving augmented BFM consolidation compared with other regimens: update of results of the Medical Research Council Trial UKALL2003
за авторством: Cutting, R, та інші
Опубліковано: (2009)

Improved Outcome for Children and Young Adults with T-Cell Acute Lymphoblastic Leukaemia (ALL): Results of the United Kingdom Medical Research Council (MRC) Trial UKALL 2003
за авторством: Vora, A, та інші
Опубліковано: (2008)

Efficacy and Toxicity of Pegylated Asparaginase in the Treatment of Children and Young Adults with Acute Lymphoblastic Leukaemia: Results of the United Kingdom Medical Research Council (MRC) Trial UKALL 2003
за авторством: Vora, A, та інші
Опубліковано: (2008)

Incidence and Outcome of Osteonecrosis in Children and Young Adults with Acute Lymphoblastic Leukaemia Treated on a Dexamethasone Containing Protocol: Results of the Medical Research Council UK Trial ALL 2003
за авторством: Vora, A, та інші
Опубліковано: (2008)

UKALL 2003, A Randomised Trial Investigating Treatment Reduction for Children and Young Adults with Minimal Residual Disease Defined Low Risk Acute Lymphoblastic Leukaemia
за авторством: Vora, A, та інші
Опубліковано: (2010)

UKALL 2003, A Randomised Trial Investigating Treatment Reduction for Children and Young Adults with Minimal Residual Disease Defined Low Risk Acute Lymphoblastic Leukaemia
за авторством: Vora, A, та інші
Опубліковано: (2010)

UKALL 2003, A Randomised Trial Investigating Treatment Reduction for Children and Young Adults with Minimal Residual Disease Defined Low Risk Acute Lymphoblastic Leukaemia
за авторством: Vora, A, та інші
Опубліковано: (2010)

Profile of Steroid Toxicity During Maintenance Treatment in Teenage and Young Adult (TYA) Patients with Acute Lymphoblastic Leukaemia (ALL)
за авторством: Tomlins, J, та інші
Опубліковано: (2012)

Variables affecting kinetics of minimal residual disease clearance in children with lymphoblastic leukaemia; Results of the United Kingdom Medical Research Council (UK MRC) protocols ALL97, ALL97/99 and ALL2003.
за авторством: Vora, A, та інші
Опубліковано: (2005)

Polymorphism in the PAI-1 (SERPINE1) gene and the risk of osteonecrosis in children with acute lymphoblastic leukemia
за авторством: Bond, J, та інші
Опубліковано: (2011)

Polymorphism in the PAI-1 (SERPINE1) gene and the risk of osteonecrosis in children with acute lymphoblastic leukemia.
за авторством: Bond, J, та інші
Опубліковано: (2011)

Delineation of Risk Factors in Paediatric Acute Lymphoblastic Leukaemia with Favourable Cytogenetics
за авторством: Moorman, A, та інші
Опубліковано: (2012)

BTG1 deletions do not predict outcome in Down syndrome acute lymphoblastic leukemia.
за авторством: Buitenkamp, T, та інші
Опубліковано: (2013)

BTG1 deletions do not predict outcome in Down syndrome acute lymphoblastic leukemia
за авторством: Buitenkamp, T, та інші
Опубліковано: (2013)

Advances in acute lymphoblastic leukemia genomics
за авторством: Christine J. Harrison, та інші
Опубліковано: (2018-06-01)

Presence of mutations in the NOTCH1 signalling pathway has a beneficial impact on outcome in paediatric T-ALL patients treated on the MRC UKALL2003 trial
за авторством: Jenkinson, S, та інші
Опубліковано: (2012)

Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21).
за авторством: Moorman, A, та інші
Опубліковано: (2007)

Advances in B-cell Precursor Acute Lymphoblastic Leukemia Genomics
за авторством: Claire Schwab, та інші
Опубліковано: (2018-08-01)