Asymmetric syntheses of fagomine and its stereoisomers

D-Fagomine (1,2,5-trideoxy-1,5-imino-d-arabino-hexitol), a naturally occurring polyhydroxylated piperidine (iminosugar), and its stereoisomers display important biological activities such as glycosidase inhibition. This review delineates both de novo asymmetric and enantiospecific syntheses of fagom...

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Bibliographic Details
Main Authors: Davies, S, Fletcher, A, Roberts, P, Thomson, J
Format: Journal article
Language:English
Published: Elsevier 2019