The genetics of FAP and FAP-like syndromes.
The presence of multiple adenomatous polyps in the large bowel confers a high lifetime risk of colorectal cancer. Although many cases of classical familial adenomatous polyposis (> 100 polyps) can be accounted for by mutations in the adenomatous polyposis coli (APC) gene, a large group of pat...
Váldodahkkit: | Lipton, L, Tomlinson, I |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
2006
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Geahča maid
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Polyclonal origin of colonic adenomas in an XO/XY patient with FAP.
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Location in the large bowel influences the APC mutations observed in FAP adenomas.
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