The genetics of FAP and FAP-like syndromes.

The presence of multiple adenomatous polyps in the large bowel confers a high lifetime risk of colorectal cancer. Although many cases of classical familial adenomatous polyposis (> 100 polyps) can be accounted for by mutations in the adenomatous polyposis coli (APC) gene, a large group of pat...

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Autori principali: Lipton, L, Tomlinson, I
Natura: Journal article
Lingua:English
Pubblicazione: 2006