Induction of CD8+ T-lymphocyte responses to a secreted antigen of Mycobacterium tuberculosis by an attenuated vaccinia virus.

Protective immunity against Mycobacterium tuberculosis infection requires the activation of mycobacterium-specific CD8+ T cells, as well as CD4+ T cells. Therefore, optimizing strategies that stimulate CD8+ T cells recognizing dominant mycobacterial antigens, including secreted proteins, may lead to...

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Príomhchruthaitheoirí: Feng, C, Blanchard, T, Smith, G, Hill, A, Britton, W
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2001