A predominantly neolithic origin for Y-chromosomal DNA variation in North Africa.
We have typed 275 men from five populations in Algeria, Tunisia, and Egypt with a set of 119 binary markers and 15 microsatellites from the Y chromosome, and we have analyzed the results together with published data from Moroccan populations. North African Y-chromosomal diversity is geographically s...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Jezik: | English |
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2004
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| _version_ | 1826267978288594944 |
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| author | Arredi, B Poloni, E Paracchini, S Zerjal, T Fathallah, D Makrelouf, M Pascali, V Novelletto, A Tyler-Smith, C |
| author_facet | Arredi, B Poloni, E Paracchini, S Zerjal, T Fathallah, D Makrelouf, M Pascali, V Novelletto, A Tyler-Smith, C |
| author_sort | Arredi, B |
| collection | OXFORD |
| description | We have typed 275 men from five populations in Algeria, Tunisia, and Egypt with a set of 119 binary markers and 15 microsatellites from the Y chromosome, and we have analyzed the results together with published data from Moroccan populations. North African Y-chromosomal diversity is geographically structured and fits the pattern expected under an isolation-by-distance model. Autocorrelation analyses reveal an east-west cline of genetic variation that extends into the Middle East and is compatible with a hypothesis of demic expansion. This expansion must have involved relatively small numbers of Y chromosomes to account for the reduction in gene diversity towards the West that accompanied the frequency increase of Y haplogroup E3b2, but gene flow must have been maintained to explain the observed pattern of isolation-by-distance. Since the estimates of the times to the most recent common ancestor (TMRCAs) of the most common haplogroups are quite recent, we suggest that the North African pattern of Y-chromosomal variation is largely of Neolithic origin. Thus, we propose that the Neolithic transition in this part of the world was accompanied by demic diffusion of Afro-Asiatic-speaking pastoralists from the Middle East. |
| first_indexed | 2024-03-06T21:02:33Z |
| format | Journal article |
| id | oxford-uuid:3b5c1a16-f67e-4d5e-b22a-dd2272a1b4f7 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:02:33Z |
| publishDate | 2004 |
| record_format | dspace |
| spelling | oxford-uuid:3b5c1a16-f67e-4d5e-b22a-dd2272a1b4f72022-03-26T14:07:06ZA predominantly neolithic origin for Y-chromosomal DNA variation in North Africa.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3b5c1a16-f67e-4d5e-b22a-dd2272a1b4f7EnglishSymplectic Elements at Oxford2004Arredi, BPoloni, EParacchini, SZerjal, TFathallah, DMakrelouf, MPascali, VNovelletto, ATyler-Smith, CWe have typed 275 men from five populations in Algeria, Tunisia, and Egypt with a set of 119 binary markers and 15 microsatellites from the Y chromosome, and we have analyzed the results together with published data from Moroccan populations. North African Y-chromosomal diversity is geographically structured and fits the pattern expected under an isolation-by-distance model. Autocorrelation analyses reveal an east-west cline of genetic variation that extends into the Middle East and is compatible with a hypothesis of demic expansion. This expansion must have involved relatively small numbers of Y chromosomes to account for the reduction in gene diversity towards the West that accompanied the frequency increase of Y haplogroup E3b2, but gene flow must have been maintained to explain the observed pattern of isolation-by-distance. Since the estimates of the times to the most recent common ancestor (TMRCAs) of the most common haplogroups are quite recent, we suggest that the North African pattern of Y-chromosomal variation is largely of Neolithic origin. Thus, we propose that the Neolithic transition in this part of the world was accompanied by demic diffusion of Afro-Asiatic-speaking pastoralists from the Middle East. |
| spellingShingle | Arredi, B Poloni, E Paracchini, S Zerjal, T Fathallah, D Makrelouf, M Pascali, V Novelletto, A Tyler-Smith, C A predominantly neolithic origin for Y-chromosomal DNA variation in North Africa. |
| title | A predominantly neolithic origin for Y-chromosomal DNA variation in North Africa. |
| title_full | A predominantly neolithic origin for Y-chromosomal DNA variation in North Africa. |
| title_fullStr | A predominantly neolithic origin for Y-chromosomal DNA variation in North Africa. |
| title_full_unstemmed | A predominantly neolithic origin for Y-chromosomal DNA variation in North Africa. |
| title_short | A predominantly neolithic origin for Y-chromosomal DNA variation in North Africa. |
| title_sort | predominantly neolithic origin for y chromosomal dna variation in north africa |
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