Upstream sequence elements enhance poly(A) site efficiency of the C2 complement gene and are phylogenetically conserved.

Poly(A) signals of mammalian pre-mRNA have been defined as an AAUAAA sequence 10-30 nt upstream of the cleavage/poly(A) site followed by a GU/U-rich element immediately downstream. However, a number of viral poly(A) signals have been shown to possess additional signals upstream of AAUAAA that increa...

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Bibliografiska uppgifter
Huvudupphovsmän: Moreira, A, Wollerton, M, Monks, J, Proudfoot, N
Materialtyp: Journal article
Språk:English
Publicerad: 1995