Continuous and discontinuous changes in the unit cell of HIV-1 reverse transcriptase crystals on dehydration.

A crystal form of HIV-1 reverse transcriptase (RT) complexed with inhibitors showed diffraction to a high-resolution limit of 3.7 A. Instability in the unit-cell dimensions of these crystals was observed during soaking experiments, but the range of this variability and consequent change in lattice o...

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Bibliographic Details
Main Authors: Esnouf, R, Ren, J, Garman, E, Somers, DO, Ross, C, Jones, E, Stammers, D, Stuart, D
Format: Journal article
Language:English
Published: 1998