With No Lysine Kinase 3 (WNK3); A Target Enabling Package

With No Lysine Kinase 3 (WNK3); A Target Enabling Package

A description of the materials and methods is included within the TEP datasheet. Kinases WNK1-4 regulate cation-chloride cotransporters via phosphorylation of SPAK and OSR1 and thereby control salt homeostasis, cell volume and blood pressure. Gain of function mutations in WNK kinases are found in Go...

Deskribapen osoa

Xehetasun bibliografikoak
Egile nagusia:	Bullock, A
Beste egile batzuk:	Pinkas, D
Formatua:	Dataset
Argitaratua:	University of Oxford 2018
Gaiak:	Structural Genomics Chemical Biology Drug Discovery

Antzeko izenburuak

With no lysine kinase 3 (WNK3); A Target Enabling Package
nork: Pinkas, D
Argitaratua: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
nork: Pinkas, D
Argitaratua: (2018)

LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package
nork: Bullock, A
Argitaratua: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
nork: Brennan, P
Argitaratua: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
nork: Brennan, P
Argitaratua: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
nork: Savitsky, P
Argitaratua: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
nork: Brennan, P
Argitaratua: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
nork: Savitsky, P
Argitaratua: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
nork: Brennan, P
Argitaratua: (2018)

Cyclin-dependent kinase 12 (CDK12), human kinase domain; a Target Enabling Package
nork: Dixon-Clarke, S
Argitaratua: (2018)

Cyclin-Dependent Kinase 12 (CDK12), human kinase domain; A Target Enabling Package
Argitaratua: (2018)

LIM domain kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
nork: Mathea, S
Argitaratua: (2018)

Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package
Argitaratua: (2018)

LIM Domain Kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
nork: Mathea, S
Argitaratua: (2018)

Human RECQL5 Helicase; A Target Enabling Package
nork: Gileadi, O
Argitaratua: (2018)

Human RECQL5 Helicase; A Target Enabling Package
nork: Newman, J
Argitaratua: (2018)

Human RECQL5 Helicase; A Target Enabling Package
nork: Newman, J
Argitaratua: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
nork: Cox, O
Argitaratua: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
Argitaratua: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
nork: Cox, O
Argitaratua: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
nork: Brennan, P
Argitaratua: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
nork: Kopec, J
Argitaratua: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
nork: Yue, W
Argitaratua: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
nork: Chu, A
Argitaratua: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
nork: Carpenter, E
Argitaratua: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
nork: Dong, Y
Argitaratua: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
nork: Newman, J
Argitaratua: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
nork: Gileadi, O
Argitaratua: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
nork: Newman, J
Argitaratua: (2018)

Inhibition of KDM4D and stabilisation of the PHF8 plant homeodomain’s transient structural states using antibodies
nork: Wolfreys, F
Argitaratua: (2017)

Zebrafish WNK lysine deficient protein kinase 1 (wnk1) affects angiogenesis associated with VEGF signaling.
nork: Ju-Geng Lai, et al.
Argitaratua: (2014-01-01)

Application of Fragment-Based Drug Discovery to Versatile Targets
nork: Qingxin Li
Argitaratua: (2020-08-01)

Analysis of multiple compound–protein interactions reveals novel bioactive molecules
nork: Hiroaki Yabuuchi, et al.
Argitaratua: (2011-03-01)

Advances in omics-based methods to identify novel targets for malaria and other parasitic protozoan infections
nork: Annie N. Cowell, et al.
Argitaratua: (2019-10-01)

Targeting the ubiquitin system by fragment-based drug discovery
nork: Cassandra Kennedy, et al.
Argitaratua: (2022-09-01)

Structural and biochemical characterization of the KLHL3-WNK kinase interaction important in blood pressure regulation.
nork: Schumacher, F, et al.
Argitaratua: (2014)

Too weak for biophysics: Prioritising and progressing fragment hits from X-ray crystallographic screening.
nork: Dubianok, Y
Argitaratua: (2021)

Structural basis for pharmacological modulation of the TRPC6 channel
nork: Yonghong Bai, et al.
Argitaratua: (2020-03-01)

Knowledge graph analytics platform with LINCS and IDG for Parkinson's disease target illumination
nork: Jeremy J. Yang, et al.
Argitaratua: (2022-01-01)

Analysis of some flavonoids for inhibitory mechanism against cancer target phosphatidylinositol 3-kinase (PI3K) using computational tool
nork: Mohd Suhail, et al.
Argitaratua: (2023-10-01)