Neutralization mechanisms of two highly potent antibodies against human enterovirus 71

Neutralization mechanisms of two highly potent antibodies against human enterovirus 71

Show other versions (1)

Despite significant advances in health care, outbreaks of infections by enteroviruses (EVs) continue to plague the Asia-Pacific region every year. Enterovirus 71 (EV71) causes hand-foot-and-mouth disease (HFMD), for which there are currently no therapeutics. Here, we report two new antibodies, A9 an...

Full description

Bibliographic Details
Main Authors:	Zhu, L, Xu, K, Wang, N, Cao, L, Wu, J, Gao, Q, Fry, E, Stuart, D, Rao, Z, Wang, J, Wang, X
Format:	Journal article
Published:	American Society for Microbiology 2018

Similar Items

Neutralization mechanisms of two highly potent antibodies against human enterovirus 71
by: Zhu, L, et al.
Published: (2018)

Neutralization Mechanisms of Two Highly Potent Antibodies against Human Enterovirus 71
by: Ling Zhu, et al.
Published: (2018-09-01)

Neutralizing Antibodies to Enterovirus 71 in Belém, Brazil
by: Maria de Lourdes C Gomes, et al.
Published: (2002-01-01)

Short-term dynamic changes in neutralizing antibodies against enterovirus 71 after vaccination
by: Shenyu Wang, et al.
Published: (2020-07-01)

Human IgG subclasses against enterovirus Type 71: neutralization versus antibody dependent enhancement of infection.
by: Rui-Yuan Cao, et al.
Published: (2013-01-01)

Development and evaluation of a pseudovirus-luciferase assay for rapid and quantitative detection of neutralizing antibodies against enterovirus 71.
by: Xing Wu, et al.
Published: (2013-01-01)

Potent antiviral agents fail to elicit genetically-stable resistance mutations in either enterovirus 71 or Coxsackievirus A16.
by: Kelly, J, et al.
Published: (2015)

Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2
by: Zhou, D, et al.
Published: (2018)

Enhanced neutralizing antibody response induced by inactivated enterovirus 71 in cynomolgus monkeys.
by: Hyun Ju In, et al.
Published: (2018-01-01)

A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
by: Wang, X, et al.
Published: (2012)

A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71
by: Wang, X, et al.
Published: (2012)

Characterization of an isotype-dependent monoclonal antibody against linear neutralizing epitope effective for prophylaxis of enterovirus 71 infection.
by: Xiao Fang Lim, et al.
Published: (2012-01-01)

Assessment of the Level of Virus Neutralizing Antibodies to Enterovirus 71 in Children in Ekaterinburg (2010–2017)
by: O. M. Olenkova, et al.
Published: (2019-05-01)

Is a monovalent vaccine against enterovirus 71 sufficient? A review of enterovirus 71 vaccine development based on enterovirus surveillance in Taiwan
by: Shu-Chun Chu, et al.
Published: (2013-09-01)

Exploration of the in vitro Antiviral Effects and the Active Components of Changyanning Tablets Against Enterovirus 71
by: Ge Q, et al.
Published: (2024-03-01)

Enterovirus 71 Maternal Antibodies in Infants, Taiwan
by: Shu-Ting Luo, et al.
Published: (2009-04-01)

Performance of detecting IgM antibodies against enterovirus 71 for early diagnosis.
by: Feihai Xu, et al.
Published: (2010-01-01)

Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody.
by: Xiaohua Ye, et al.
Published: (2016-03-01)

VP1 of Enterovirus 71 Protects Mice Against Enterovirus 71 and Coxsackievirus B3 in Lethal Challenge Experiment
by: Fang-Hong Chen, et al.
Published: (2019-11-01)

Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71
by: Kuan-Ying A. Huang, et al.
Published: (2020-10-01)

Outbreaks of enterovirus 71 infection
by: AbuBakar, Sazaly, et al.
Published: (2000)

Neutralizing antibody response in the patients with hand, foot and mouth disease to enterovirus 71 and its clinical implications
by: Zhu Liye, et al.
Published: (2011-06-01)

Development of Novel Vaccines against Enterovirus-71
by: Pinn Tsin Isabel Yee, et al.
Published: (2015-12-01)

Protection against enterovirus 71 with neutralizing epitope incorporation within adenovirus type 3 hexon.
by: Xingui Tian, et al.
Published: (2012-01-01)

The Immungenicity and Cross-Neutralizing Activity of Enterovirus 71 Vaccine Candidate Strains
by: Xia Xiao, et al.
Published: (2021-08-01)

A novel universal neutralizing monoclonal antibody against enterovirus 71 that targets the highly conserved "knob" region of VP3 protein.
by: Tanja K Kiener, et al.
Published: (2014-01-01)

In vivo time-related evaluation of a therapeutic neutralization monoclonal antibody against lethal enterovirus 71 infection in a mouse model.
by: Zhiqun Li, et al.
Published: (2014-01-01)

Receptors for enterovirus 71
by: Seiya Yamayoshi, et al.
Published: (2014-01-01)

Enterovirus 71 in Taiwan
by: Luan-Yin Chang
Published: (2008-08-01)

COPI is required for enterovirus 71 replication.
by: Jianmin Wang, et al.
Published: (2012-01-01)

Correction: Protection against Enterovirus 71 with Neutralizing Epitope Incorporation within Adenovirus Type 3 Hexon
Published: (2012-01-01)

Correction: Protection against Enterovirus 71 with Neutralizing Epitope Incorporation within Adenovirus Type 3 Hexon.
by: Xingui Tian, et al.
Published: (2012-01-01)

Antiviral Effect of Matrine against Human Enterovirus 71
by: Jiangning Liu, et al.
Published: (2012-08-01)

Anti-Enterovirus 71 Agents of Natural Products
by: Liyan Wang, et al.
Published: (2015-09-01)

Neutralizing antibodies against enteroviruses in patients with hand, foot and mouth disease
by: Nguyet, LA, et al.
Published: (2020)

Milrinone in Enterovirus 71 Brain Stem Encephalitis
by: SHIH-MIN eWANG, et al.
Published: (2016-03-01)

The cross-neutralizing activity of enterovirus 71 subgenotype c4 vaccines in healthy chinese infants and children.
by: Qunying Mao, et al.
Published: (2013-01-01)

Challenges to licensure of enterovirus 71 vaccines.
by: Min-Shi Lee, et al.
Published: (2012-01-01)

Enterovirus 71 outbreak, Brunei
by: AbuBakar, Sazaly, et al.
Published: (2009)

Enterovirus A71 Vaccines
by: Mei-Ling Li, et al.
Published: (2021-02-01)