Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A.
The major histocompatibility complex (MHC) on chromosome 6 is associated with susceptibility to more common diseases than any other region of the human genome, including almost all disorders classified as autoimmune. In type 1 diabetes the major genetic susceptibility determinants have been mapped t...
Autores principales: | Nejentsev, S, Howson, J, Walker, N, Szeszko, J, Field, S, Stevens, H, Reynolds, P, Hardy, M, King, E, Masters, J, Hulme, J, Maier, L, Smyth, D, Bailey, R, Cooper, J, Ribas, G, Campbell, R, Clayton, D, Todd, J |
---|---|
Formato: | Journal article |
Lenguaje: | English |
Publicado: |
2007
|
Ejemplares similares
-
Structure and function of the human MHC class Ib molecules HLA-E, HLA-F and HLA-G.
por: O'Callaghan, C, et al.
Publicado: (1998) -
A novel and major association of HLA-C in Graves' disease that eclipses the classical HLA-DRB1 effect.
por: Simmonds, M, et al.
Publicado: (2007) -
HLA heterozygosity contributes to susceptibility to rheumatoid arthritis.
por: Wordsworth, B, et al.
Publicado: (1992) -
Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis.
por: Fakiola, M, et al.
Publicado: (2013) -
The HLA class II component of susceptibility to rheumatoid arthritis.
por: Wordsworth, B, et al.
Publicado: (1992)