Activation of Salmonella Typhi-specific regulatory T cells in typhoid disease in a wild-type S. Typhi challenge model.

Salmonella Typhi (S. Typhi), the causative agent of typhoid fever, causes significant morbidity and mortality worldwide. Currently available vaccines are moderately efficacious, and identification of immunological responses associated with protection or disease will facilitate the development of imp...

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Autori principali: McArthur, M, Fresnay, S, Magder, L, Darton, T, Jones, C, Waddington, C, Blohmke, C, Dougan, G, Angus, B, Levine, M, Pollard, A, Sztein, M
Natura: Journal article
Lingua:English
Pubblicazione: Public Library of Science 2015