Hot spots in Tcf4 for the interaction with beta-catenin.

Hot spots in Tcf4 for the interaction with beta-catenin.

The interaction of beta-catenin with T-cell factor (Tcf) 4 plays a central role in the Wnt signaling pathway and has been discussed as a possible site of intervention for the development of anti-cancer drugs. In this study, we performed Ala-scanning mutagenesis of all Tcf4 residues in the Tcf-beta-c...

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Bibliographische Detailangaben
Hauptverfasser:	Fasolini, M, Wu, X, Flocco, M, Trosset, J, Oppermann, U, Knapp, S
Format:	Journal article
Sprache:	English
Veröffentlicht:	2003

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