Hot spots in Tcf4 for the interaction with beta-catenin.

Hot spots in Tcf4 for the interaction with beta-catenin.

The interaction of beta-catenin with T-cell factor (Tcf) 4 plays a central role in the Wnt signaling pathway and has been discussed as a possible site of intervention for the development of anti-cancer drugs. In this study, we performed Ala-scanning mutagenesis of all Tcf4 residues in the Tcf-beta-c...

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Chi tiết về thư mục
Những tác giả chính:	Fasolini, M, Wu, X, Flocco, M, Trosset, J, Oppermann, U, Knapp, S
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2003

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