Effects of vaccinia virus anti-inflammatory protein 35K and TIMP-1 gene transfers on vein graft stenosis in rabbits.
BACKGROUND: Vein graft stenosis is a common problem after bypass surgery. Vein grafts are ideal targets for gene therapy because transduction can be made ex vivo before grafting. Since chemokines and inflammatory factors are involved in vein graft thickening, we tested a hypothesis that the vaccini...
Main Authors: | Puhakka, H, Turunen, P, Gruchala, M, Bursill, C, Heikura, T, Vajanto, I, Greaves, D, Channons, K, Ylä-Herttuala, S |
---|---|
格式: | Journal article |
語言: | English |
出版: |
2005
|
相似書籍
-
Adenovirus-mediated gene transfer of Lp-PLA2 reduces LDL degradation and foam cell formation in vitro
由: Päivi Turunen, et al.
出版: (2004-09-01) -
A membrane-bound vaccinia viral protein 'mem35k' blocks CC-chemokine induced cell migration and CC-chemokine activity in vitro
由: Bursill, C, et al.
出版: (2005) -
Adenoviral mediated delivery of a vaccinia viral protein (35K) blocks CC-chemokine activity in vitro and in vivo and may therefore be a useful therapeutic strategy to reduce the initiation and progression of CC-chemokine induced atherosclerosis
由: Bursill, C, et al.
出版: (2003) -
Rabbit atherosclerotic lesions express scavenger receptor AIII mRNA, a naturally occurring splice variant that encodes a non-functional, dominant negative form of the macrophage scavenger receptor.
由: Hiltunen, T, et al.
出版: (2001) -
Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression.
由: Margreet R de Vries, et al.
出版: (2012-01-01)