Effects of vaccinia virus anti-inflammatory protein 35K and TIMP-1 gene transfers on vein graft stenosis in rabbits.

BACKGROUND: Vein graft stenosis is a common problem after bypass surgery. Vein grafts are ideal targets for gene therapy because transduction can be made ex vivo before grafting. Since chemokines and inflammatory factors are involved in vein graft thickening, we tested a hypothesis that the vaccini...

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Những tác giả chính: Puhakka, H, Turunen, P, Gruchala, M, Bursill, C, Heikura, T, Vajanto, I, Greaves, D, Channons, K, Ylä-Herttuala, S
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2005