Inositol adenophostin: convergent synthesis of a potent agonist of D-myo-inositol 1,4,5-trisphosphate receptors
D-myo-Inositol 1,4,5-trisphosphate receptors (IP3Rs) are Ca2+ channels activated by the intracellular messenger inositol 1,4,5-trisphosphate (IP3, 1). The glyconucleotide adenophostin A (AdA, 2) is a potent agonist of IP3Rs. A recent synthesis of D-chiro-inositol adenophostin (InsAdA, 5) employed su...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
American Chemical Society
2020
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