mRNA quality control goes transcriptional.
Eukaryotic mRNAs are extensively processed to generate functional transcripts, which are 5' capped, spliced and 3' polyadenylated. Accumulation of unprocessed (aberrant) mRNAs can be deleterious for the cell, hence processing fidelity is closely monitored by QC (quality control) mechanisms...
Autors principals: | Kilchert, C, Vasiljeva, L |
---|---|
Format: | Journal article |
Idioma: | English |
Publicat: |
2013
|
Ítems similars
-
Regulation of mRNA levels by decay-promoting introns that recruit the exosome specificity factor Mmi1
per: Kilchert, C, et al.
Publicat: (2015) -
Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1
per: Cornelia Kilchert, et al.
Publicat: (2015-12-01) -
The regulation and functions of the nuclear RNA exosome complex
per: Kilchert, C, et al.
Publicat: (2016) -
lncRNA recruits RNAi and the exosome to dynamically regulate pho1 expression in response to phosphate levels in fission yeast.
per: Shah, S, et al.
Publicat: (2014) -
DSIF factor Spt5 coordinates transcription, maturation and exoribonucleolysis of RNA polymerase II transcripts
per: Kuś, K, et al.
Publicat: (2025)